If you are taking this medicine, it is very crucial that your healthcare Skilled know For anyone who is taking any from the medicines stated down below. The following interactions have been selected on the basis of their potential significance and therefore are not essentially all-inclusive.
Make certain you know the way to take hydrocodone/acetaminophen and what other drugs you must prevent taking with it. See also Drug Interactions section. Get medical help immediately if any of those incredibly significant side effects happen: sluggish/shallow breathing, abnormal lightheadedness, critical drowsiness/dizziness, problem waking up.
diazepam intranasal and hydrocodone both raise sedation. Stay away from or Use Alternate Drug. Restrict use to patients for whom different treatment options are inadequate
Mixed opioid agonists/antagonists and partial opioid agonists may reduce the analgesic effect of hydrocodone and/or precipitate withdrawal symptoms in opioid tolerant patients. .
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Reserve concomitant prescribing of those drugs in patients for whom other treatment selections are inadequate. Restrict dosages and durations to the minimal expected. Monitor carefully for signs of respiratory depression and sedation.
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Hydrocodone may perhaps cause slowed or stopped breathing, Specially over the to start with 24 to seventy two several hours of your treatment and any time your dose is improved. Your health care provider will monitor you cautiously in the course of your treatment. Your medical professional will adjust your dose to manage your pain and reduce the danger that you'll expertise significant breathing challenges. Convey to your medical professional should you have or have at any time experienced slowed respiration or asthma. Your physician will probably let you know to not take hydrocodone. Also explain to your health practitioner in the event you have or have ever had lung disease like chronic obstructive pulmonary disease (COPD; a group of diseases that affect the lungs and airways), a head injuries, a brain tumor, or any problem that improves the amount of pressure in your Mind.
methylene blue will increase toxicity of hydrocodone by serotonin levels. Prevent or Use Alternate Drug. MAOI interactions with opioids might manifest as serotonin syndrome or opioid toxicity (eg, respiratory depression, coma). Opioids are certainly not recommended for patients taking MAOIs or within 14 times of stopping MAOIs. If urgent opioid treatment essential, use test doses and frequent titration of little doses to treat pain while intently monitoring blood pressure and signs and symptoms of CNS and respiratory depression.
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Skip the missed dose and proceed your standard dosing schedule. Tend not to take far more than just one dose of hydrocodone extended-release capsules in 12 hours or extended-release tablets in 24 hrs.
asenapine transdermal and hydrocodone equally enhance sedation. Prevent or Use Alternate Drug. Restrict use to patients hydrocodone effects for whom choice treatment selections are insufficient
If someone has overdosed and has serious symptoms for instance passing out or problems respiratory, give them naloxone if obtainable, then connect with 911. If the person is awake and it has no symptoms, contact a poison Regulate center without delay.
Although it helps many people, this medication could sometimes cause addiction. This possibility may very well be higher in the event you have a substance use disorder (for example overuse of or addiction to drugs/alcohol).